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Research
Books and Book Reviews Sexually Transmitted Infections and Sexually Transmitted Diseases Book Description (from Amazon.com)
Mucocutaneous Manifestations of Viral Diseases: Book Description (From Amazon.com) The only existing text to address issues of skin manifestations of viral disease, Mucocutaneous Manifestations of Viral Diseases explores the diagnosis, treatment, and pathogenesis of viral diseases that infiltrate the skin and affiliated mucous membranes.
Clinical and Basic Immunodermatology Editorial Review This volume is a welcome addition to the somewhat sparsely populated list of current texts in immunodermatology. The importance of the immune system in the mechanisms underlying or contributing to the pathogenesis of many skin diseases has long been recognized, and any perusal of current journals reveals a seemingly exponential growth in the body of information in the field. The editors and the numerous expert contributors have valiantly addressed the task of presenting key new findings in the context of previous knowledge and clinical disease. The first of the four sections of this book comprises 11 chapters that include overviews of the major components of systemic and cutaneous immunology. It is clear at the outset that the authors assume that the reader possesses at least a foundational knowledge and understanding of the field. This section opens with a thorough discussion of the production and function of the cytokines and chemokines that mediate the numerous functions of the immune system, which are increasingly being examined for their potential therapeutic benefit in many diseases. The section continues with reviews of several key aspects of innate and specific immunity, with particularly informative chapters on the function of T lymphocytes and their numerous subsets, and photoimmunology. A topic notable for its absence is genetics—particularly a discussion of genetic association and predisposition toward disease. Some specific information is found in the clinical sections of the book; for example, the chapters on psoriasis and atopic dermatitis include short explanations of genetic analyses and the detection of candidate disease susceptibility genes and gene polymorphisms. The other sections, which comprise the majority of the volume, are focused on the immunologic aspects of skin diseases and immunotherapeutic modalities. The list of diseases discussed verges on the encyclopedic, but emphasis is placed on the most common diseases, including inflammatory skin diseases, infections, and malignancies. This section also includes a concise overview of HIV/AIDS and its cutaneous manifestations, and a useful chapter on drug eruptions and underlying immune mechanisms. Autoimmune diseases and immunodeficiency and other immune-associated skin diseases are afforded their own section; the discussions of the bullous diseases are particularly well written. The chapter on primary immunodeficiencies is both instructive and concise. Finally, the immunopharmacology section of this text is excellent, providing timely information on approved and emerging biologic response modifiers and traditional adjuvant and antiinflammatory agents. Despite some inevitable differences in style between contributing authors, this text is easy to read and understand. Relatively few clinical photographs are included, but there are many excellent explanatory diagrams that enhance the text, and the uniform style of these illustrations lends well to the continuity of concepts. Each chapter begins with a useful outline of key points to be discussed and concludes with an exhaustive bibliography for those who wish to explore a topic in greater depth. This text, in conjunction with current primary literature, should be an excellent teaching tool for dermatology residents and fellows, and a valuable reference resource for clinicians. A paperback edition of this volume has also recently been published. Book Description (from Amazon.com)
Mucosal Immunology and Virology Book Description (from Amazon.com)
Tropical Dermatology Editorial Review During the past few decades, there has been an explosion of interest in tropical medicine among the dermatology community. One likely explanation is that dermatologists in Western countries are encountering more and more patients with tropical diseases, either imported during international travel or related to a progressively more multiethnic society (immigrants, refugees, or adoptees). Although in tropical areas such diseases are usually well known and easily recognized by experienced physicians, at our latitudes the rarity of and unfamiliarity with them may lead to problems of differential diagnosis and, consequently, improper management. Tropical Dermatology represents both a practical and comprehensive guide to the mucocutaneous manifestations of tropical diseases. This book is concise enough to be read cover-to-cover, yet authoritative enough to be used as a reference as well. Moreover, the huge number of color images and figures serve as a pseudo-atlas and facilitate an understanding of the various topics. Apart from the expected, systematic, and more or less conventional description of the most common tropical infections and infestations, this manual shines with its section dedicated to noninfectious conditions. Environmental causes of dermatitis, which are often missing from other texts, are included here, and may represent a recurrent source of cutaneous problems in returned travelers. Contact to tropical plants, for example, can cause mechanical injury, primary irritant (toxic) dermatitis, allergic phytodermatitis, or contact urticaria. Taking into account the frequency of exotic-sea vacations and the popularity of tropical aquariums, another section of the book addresses the dermatologic manifestations of marine and freshwater exposures to various organisms, such as bacteria, sponges, coelenterates, worms, echinoderms, mollusks, and fish. One nice feature of this book faces the issues of the prospective traveler. This section prepares the reader to counsel travelers about potential dermatoses, infections, and environmental hazards specific to the area of destination, and discusses general preventive measures, including appropriate vaccinations and prophylaxis. Moreover, it offers practical and useful recommendations on what might be considered for a travel medical kit. Because tropical arthropods act repeatedly as vectors of disease carrying bacterial, protozoan, and helminthic pathogens, this section details practical information on how to prevent bites and stings (including the use of repellents, insecticides, bed nets, and infrastructure improvement). General preventive measures for travelers concerning food, beverages, poisons, weather, altitude, walking, and safe sexual practices are also included. In addition, there is helpful posttravel advice aimed at facilitating early recognition of signs or symptoms of travel-related illnesses. It seems increasingly important that current dermatologists become acquainted with tropical mucocutaneous diseases to promptly diagnose and consequently avoid potential complications. Tropical Dermatology represents a valuable tool that guides a thorough approach to and treatment of patients with tropical diseases. Book Description (from Amazon.com)
Editorial Review Purpose: To enhance clinicians' and scientists' knowledge and understanding of current management strategies for viral diseases and the prospects of future advances. Antiviral therapy is an important subject because several major viral infections lack adequate therapy. In some situations, treatments exist, but they are limited by substantial toxicity. Content: The book reviews recent advances in antiretroviral therapies, general antiviral therapies, antiviral vaccines, and immunotherapies that are used to prevent and treat viral infections. Chapter 1 reviews the current status of antiviral therapy. It discusses future needs and highlights the importance of public health measures and vaccine development. The chapter's introduction discusses customized vaccines and antiviral therapy based on assessment of singlenucleotide polymorphisms. Chapter 2 provides an excellent overview of current antiretroviral agents and the mechanisms of action and adverse events of the major agents. Chapter 3 is an extensive overview of the major nonantiretroviral and antiviral agents, including those that work against herpesviruses, respiratory viruses, human papillomavirus, and hepatitis B and C viruses. In addition, this chapter discusses immunomodulation agents, such as interferon-x and imiquimod. Chapter 4, the final chapter, discusses vaccines and immunotherapies, current vaccines against viruses, and investigational products. The chapter briefly addresses polyclonal intravenous immune globulin and monoclonal antibodies. It also summarizes the recommended immunization schedule for adults issued by The Advisory Committee on Immunization Practices and provides the childhood and adolescent schedules for vaccination. Highlights: This is a brief but excellent, well-referenced review of antiviral therapy. It puts the current state of knowledge in perspective, while highlighting the directions for future work. The material is presented systematically, is easy to read and understand, and includes well-organized tables. It spans from molecular structures and mechanisms of action to practical aspects of drug availability, and it discusses the economic impact of antiviral treatment. Finally, the book provides a unique clinician-investigator perspective. Limitations: While the book is comprehensive, some areas lack details. It is difficult to capture all aspects of antiviral management in a book of this size. More details in areas such as vaccination might further improve future editions of this text. Similarly, replacing the current schematic figures with better-quality illustrations might be more reader-friendly and instructive. Related reading: Several related texts could supplement specific topics in the book: Knipe and colleagues' Fields Virology, 4th edition (Lippincott Williams & Wilkins, 2001), and Stiehm's Immunologic Disorders in Infants & Children, 5th edition (WB Saunders, 2004). In addition, up-to-date information on the evolving field of antiretroviral agents is available from the U.S. Department of Health and Human Services (http://aidsinfo.nih.gov/drugs). Book Description (from Amazon.com)
Editorial Reviews Since the 1980s, human immunodeficiency virus (HIV), viral hepatitis, infection with the Ebola and Marburg viruses, and the threat of smallpox have had a major effect on world health. The increasing rate of travel to and from both easily accessible and remote regions of the world, the growing number of medically compromised persons, and the increasing prevalence of previously unknown or rare viruses have had a considerable effect on clinical practice. Thus, this easy-to-read book on viruses is timely and fills a void for practitioners everywhere. The editor of the book, Dr. Stephen K. Tyring, a leader in the field of cutaneous manifestations of viral diseases, has authored or coauthored six of the chapters. In general, each of the 23 chapters is well written and concise. The first two chapters, which introduce the topics of cutaneous virology and cutaneous resistance, will permit clinicians to master the basic concepts of 21st-century virology and viral immunology. Each of the succeeding 21 chapters focuses on one family or species of viruses. The layout of each chapter is user friendly and tailored to the visual as well as the traditional learner. Complex immunologic mechanisms are made clear. Each chapter begins with a definition of the virus under consideration, followed by a short history and a discussion of the incidence, pathogenesis, and clinical manifestations of the viral disease. Each chapter contains excellent charts and diagrams illustrating the geographic distribution, the taxonomy, and the mechanism of transmission, including host, vector, and animal reservoirs. Tables enhance the concise but comprehensive clinical data and summarize the clinical manifestations, differential diagnoses, key distinguishing features, and treatment. A reference list of useful articles appears at the end of each chapter. The extensive collection of color photographs is the highlight of this book. For example, the chapter on human herpesvirus 8 illustrates in vivid color not only a dozen clinical presentations of Kaposi's sarcoma but also other conditions that should be considered in the differential diagnosis. The chapter on poxviruses illustrates excellent examples of smallpox and also examples of vaccination-site reactions, localized dissemination, autoinoculation of vaccinia, and eczema vaccinatum. Mucocutaneous Manifestations of Viral Diseases is a clearly written and well-illustrated single-volume textbook. It is ideal for hospitalists, dermatologists, infectious-disease specialists, pediatricians, internists, and family practitioners. Copyright © 2003 Massachusetts Medical Society. All rights reserved. The New England Journal of Medicine is a registered trademark of the MMS. From Book News, Inc.
Editorial Reviews The viruses responsible for human papillomavirus (HPV) infection have long been known to cause banal, benign lesions such as cutaneous warts and anogenital condylomas, which occur in most individuals at some time in their lives. More recently, the discovery of HPV involvement in the genesis of malignant lesions (eg, squamous cell carcinomas of the cervix and the skin) has generated considerable interest among clinicians and research scientists. These viruses long eluded laboratory culture and were therefore difficult to study. Progress in molecular biology techniques, however, has allowed considerable advances in our understanding of their nature and their role in the development of mucocutaneous benign and malignant diseases; and this understanding, in turn, generates hope for the production and use of prophylactic vaccination. The aim of this book, written principally for clinicians, was to present current research ideas alongside present-day approaches to patient management—essentially, it provides a "gene-to-clinic" approach. The book contains 13 chapters totaling 153 pages of text, and is divided into 4 parts: (1) Introduction; (2) molecular and cellular aspects ("Biology of Human Papillomaviruses," "Molecular Mechanisms of HPV-Associated Oncogenesis," and "Immune Response to HPV"); (3) lesions and diseases ("Cutaneous Warts," "Genital Warts," "Human Papillomavirus and Oral Disease," "Respiratory Papillomatosis," "Epidermodysplasia Verruciformis," "Human Papillomavirus and Immunosuppression"); and (4) prospects ("Antivirals," "Vaccines," and "Basic Research"). The chapters were written by a panel of 18 renowned scientists, mostly from the United States and the United Kingdom , actively involved in clinical and basic research on HPV. The chapters are illustrated with many color photographs, diagrams, and tables. These are of high quality and are documented by a reasonable amount of recent relevant references, which facilitates the understanding of the text. The chapters covering HPV biology provide a good overview to physicians who may not be familiar with this topic; those dealing with diseases caused by HPV are similarly instructive and provide useful therapeutic guidelines. The last part of the book summarizes current and future modes of treatment, and discusses the prospect of prophylactic vaccinations. Overall, this book nicely covers aspects of the biological changes and diseases associated with HPV. It is pleasant to read, and will certainly be useful to all physicians, be they dermatologists, pediatricians, urologists, otolaryngologists, or dentists, who have to deal with HPV infections. It will also be of interest to scientists involved in research related to HPV. Book Description (from Amazon.com) This book combines a discussion of up-to-date research findings with clinical features, the treatments presently available and future directions for therapy. It is aimed principally at clinicians, who need to keep up to date with the basic science but also want practical information to apply to clinical cases, and will also appeal to scientists needing a clinical background to their research. In order to achieve this balance, the well respected editors have recruited contributions from a number of scientists eminent in their particular areas of HPV research, as well as from clinicians with wide experience in dealing with the medical challenges of treating warts. The book will be essential reading for trainee and practicing dermatologists, and a valuable shelf reference for immunologists and other researchers and clinicians with an interest in HPV infection.
From Book News, Inc. Resources CCS In the News: KTRK (ABC 13 News): New treatments offer help, hope for psoriasis patients (Jan 22, 2010) Texas Organizations Herpes Support Groups: Clear Lake HSV and HPV Support Group Ft. Worth HELP Frontera HELP Houston HELP San Antonio HELP Psoriasis Support Groups Dallas, Texas Houston Pasadena, Texas San Antonio, Texas San Antonio, Texas National Organizations HIV Treatment/Information Organizations Psoriasis Organizations Shingles Post-Herpetic Neuralgia
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